The oxidation of serine using N-bromosuccinimide (NBS) has been studied at fix pH value. The reaction presents a first-order reaction with respect to both substrate and oxidant. It is noted that the rate of reaction increases with increasing the palladium ion concentration. The addition of the reaction product (succinimide) affects the oxidation reaction rate. The protonated Br+ or NBrS and NBrS are used to be the reactive species of the N-bromosuccinimide. Furthermore, intermediate compounds are noticed through the reaction. Finally, a mechanism for the oxidation reaction is suggested in this work.
Keywords: Kinetics, Oxidation process, Amino acid, N-bromosuccinimide.
International Journal of Drug Delivery Technology (2022); DOI: 10.25258/ijddt.12.2.54
How to cite this article: Salman NY. Kinetics Study of the Reaction between Serine and N-Bromosuccinimide in the Presence of Palladium (Pd2+). International Journal of Drug Delivery Technology. 2022;12(2):771-774.
Source of support: Nil.
Conflict of interest: None
Kinetics Study of the Reaction between Serine and N-Bromosuccinimide in the Presence of Palladium (Pd2+)