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Vitamin D status and glycemic control in patients with type 2 diabetes mellitus

Diabetes mellitus type 2 represent significant problem for health care givers because of its huge prevalence. The prevalence of diabetes mellitus is expected to elevatedby 2030 to as high as 366 million diabetic patients.The clue for non-skeletal impact of vitamin D become increasing suggesting the potential benefit in many diseases related to cardiac system, immunity disorders and diabetes mellitus type 2.  The possible beneficial effect of vitamin D in glycemic control is declared after the seasonal differentiation in the glycemic control where the winter season represent poor glycemic control due to prevalence of hypovitaminosis. From other hand, there is many cross-sectional studies indicate the inverse relationship between the status of vitamin D and glycemic control. currently, other types of studies like observational and interventional articles add another evidence for beneficial role of status of vitamin D on the control of glycaemia by its results about the  relationship between occurrence of diabetes mellitus type 2 and status of vitamin D.  In addition to its effect on homeostasis of calcium and phosphate by regulation of absorption of calcium and phosphate, as a pro-hormone, vitamin D has significant role in insulin secretion. The systematic review article that performed by Ass. lec.Alishlash found that thepatient’s vitamin D status can has important impact on the pathogenesis of T2DM. The diabetic patients with poor indices of glycaemia has higher prevalence of decreased vitamin D level referring to potential benefit of vitamin D in correction of such indices.

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