الرئيسية / الفعاليات العلمية / بحوث / Abstract. Theoretical measurements of pharmaceutical compound 5-fluorouracil (5-FU) drug

Abstract. Theoretical measurements of pharmaceutical compound 5-fluorouracil (5-FU) drug

and the theoretical activities were calculated by QSAR–Hansch model as a function of the

geometrical properties. The extracted results of a new derivatives shown how can the increase of

minimum effective concentration in a new designed derivatives of

5-FU derivatives have a different activities (the minimum effective

concentration; C), were studied depending on geometrical properties. Then, the straight line

equations (Y= a X ∓ b) and square root of correlation factor (R2

) can be extracted by plot of

effective concentration logarithm [log (1/C)] for 5–FU derivatives versus each one of

geometrical properties. This matter led to correct the geometrical properties of 5-FU derivatives

and formulating of quantitative structure activity relationship (QSAR) by Hansch model. The

geometrical properties. The extracted results of a new derivatives shown how can the increase of

minimum effective concentration in a new designed derivatives of 5-FU drug (as a starting

martial).

 

 

شاهد أيضاً

The Nephroprotective Effects of Moringa Oleifera Extract against Contrast Induced Nephrotoxicity

Objectives: The present research has been conducted to assess the Nephroprotective effects of the Moringa …

اترك تعليقاً

لن يتم نشر عنوان بريدك الإلكتروني. الحقول الإلزامية مشار إليها بـ *