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The role of mTOR signaling pathway in regulating cancer

A principle hallmark of all cells is the ability to adapt and sense their environment in order to survive in a constantly changing environment. Part of this adaptation in most of organisms needs being able to transition quickly between catabolic and anabolic states based on the nutrients availability. This tolerates lets a cell to keep away from death during times of nutrient depletion by consumption dropping along with allowing a cell to proliferate by consumption increasing once nutrients are abundant and growth is beneficial to the organism. A kinase complex called mTORC1 is considered one of the main mechanisms for many organisms to

 

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